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Pilot Study of a Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Adenocarcinoma

Summary

The purpose of this pilot study is to evaluate the feasibility, safety, and immune response to a personalized neoantigen vaccine combined with retifanlimab for MMR-p mCRC and mPDAC patients with measurable disease following first-line FOLFIRINOX/FOLFOXIRI (FFX).

General Information

NCT#: NCT04799431
Study ID: J2114
Trial Phase: Pilot

Trial Sponsor: Sidney Kimmel Comprehensive Cancer Center
Therapies Used in This Trial: Hiltonol®, Retifanlimab

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Site Information


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