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Phase Ib/IIa Open-label Study of NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Patients With Relapsed/Refractory Advanced Solid Tumors, including Pancreatic Cancer

Summary

The main purposes of Phase 1b of this study are to determine the following in participants with advanced solid tumors: - Safety and tolerability of NT-I7 in combination with pembrolizumab - Maximum Tolerated Dose (MTD) and/or the Recommended Phase 2 Dose (RP2D) The main purpose of Phase 2a of this study is to assess the preliminary anti-tumor activity of NT-I7 in combination with pembrolizumab in participants with checkpoint inhibitor (CPI) treated and naïve relapsed and refractory tumors.

General Information

NCT#: NCT04332653
Study ID: NIT-110 (PNA60)
Trial Phase: Phase I/II

Trial Sponsor: NeoImmuneTech Inc.
Therapies Used in This Trial: Pembrolizumab, NT-I7

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Site Information


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