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Phase I/II Study of Neratinib and Divalproex Sodium (Valproate) in Advanced Solid Tumors, With an Expansion Cohort in Ras-Mutated Cancers

Summary

The purpose of this phase I/II study is to determine the recommended phase II dose (RP2D) of the combination of neratinib and sodium valproate when given to patients with advanced solid tumors.

General Information

NCT#: NCT03919292
Study ID: MCC-17-13821
Trial Phase: Phase I/II

Trial Sponsor: Virginia Commonwealth University, Puma Biotechnology, Inc.
Therapies Used in This Trial: Neratinib, Sodium valproate

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