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Phase II Evaluation of the Effect of 2 Versus 6 Hour Oxaliplatin Infusions on Neuropathy and Pharmacokinetics in Patients With Gastrointestinal Cancers

Summary

The purpose of this phase II trial is to study how well giving oxaliplatin over 6 hours works in treating nerve damage in patients with gastrointestinal cancers. Oxaliplatin can cause side effects such as nerve damage that may delay or reduce the dose of oxaliplatin. Giving oxaliplatin over a longer period of time (6 hours) may prevent or delay the development of nerve damage, which may keep patients on standard doses of chemotherapy longer, without having to delay treatment.

General Information

NCT#: NCT03800693
Study ID: IRB00106610
Trial Phase: Phase II

Trial Sponsor: Emory University
Therapies Used in This Trial: Fluorouracil, Oxaliplatin, Leucovorin, FOLFOX

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