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Phase I Study of Human Chimeric Antigen Receptor Modified T Cells (CAR T Cells) in Patients With Pancreatic Cancer

Summary

The purpose of this phase I study is to evaluate an immunotherapy approach to pancreatic cancer, where patients' own immune cells are engineered to treat their cancer. Specifically, the study seeks to determine the safety and feasibility of intravenous administration of transduced huCART-meso cells in patients with histologically confirmed unresectable or metastatic pancreatic adenocarcinoma both with and without cyclophosphamide as lymphodepleting chemotherapy.

General Information

NCT#: NCT03323944
Study ID: 827664
Trial Phase: Phase I

Trial Sponsor: SU2C - Stand Up to Cancer, University of Pennsylvania Abramson Cancer Center, Lustgarten Foundation
Therapies Used in This Trial: Chimeric Antigen Receptor Modified T Cells (CART-meso)

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