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Phase Ib/II Open-label, Multicenter, Clinical Study to Evaluate the Safety and Efficacy of CD40 Agonistic Monoclonal Antibody (APX005M) Administered Together With Gemcitabine and Nab-Paclitaxel With or Without PD-1 Blocking Antibody (Nivolumab) in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Summary

The purpose of this phase Ib/II trial is to evaluate the safety and effectiveness of APX005M with gemcitabine and nab-paclitaxel with or without nivolumab in patients with metastatic pancreatic adenocarcinoma.

General Information

NCT#: NCT03214250
Study ID: PICI0002 UPCC 11217
Trial Phase: Phase I/II

Trial Sponsor: Parker Institute for Cancer Immunotherapy
Therapies Used in This Trial: Nab-paclitaxel, Gemcitabine, Nivolumab, APX005M

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