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Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A 1101 Patients

Summary

The purpose of this phase I/II trial is to determine if anti-KRAS G12 V mTCR cells are safe and can shrink tumors. HLA and biomarker testing to determine if patient is eligible will be done during screening for the trial; however, prior reports are encouraged.

General Information

NCT#: NCT03190941
Study ID: 170113 / 17-C-0113
Trial Phase: Phase I/II

Trial Sponsor: National Cancer Institute (NCI)
Therapies Used in This Trial: Cyclophosphamide, Aldesleukin, Fludarabine, anti-KRAS G12V mTCR cells

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Site Information


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