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Phase Ib/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in Participants With Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Summary

The purpose of this phase I/II study is to find a safe dose of LMB-100 with a fixed standard dose of nab-paclitaxel in people with advanced pancreatic cancer, and to see how well the combination of the two drugs reduce tumor size.

General Information

NCT#: NCT02810418
Study ID: 160128
Trial Phase: Phase I/II

Trial Sponsor: National Cancer Institute (NCI)
Therapies Used in This Trial: Nab-paclitaxel, LMB-100

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