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Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Cancers Plus the Administration of Pembrolizumab at Time of Progression

Summary

5/21/2018 NOTE: This trial is currently enrolling into the TIL with pembrolizumab at progression cohort. The purpose of this phase II trial is to see if these specifically selected tumor fighting cells can cause digestive tract, urothelial, breast, or ovarian/endometrial tumors to shrink and to see if this treatment is safe.

General Information

NCT#: NCT01174121
Study ID: 10-C-0166
Trial Phase: Phase II

Trial Sponsor: National Cancer Institute (NCI)
Therapies Used in This Trial: Cyclophosphamide, Aldesleukin, Fludarabine, CD8+ Enriched Autologous Tumor-Infiltrating Lymphocytes, Pembrolizumab

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